It was characterized by its quiet simplicity and gentleness. Episodes did not have a plot, and consisted of Rogers speaking directly to the viewer about various issues, taking the viewer on tours of factories, demonstrating experiments, crafts, and music, and interacting with his friends. The half-hour episodes were punctuated by a puppet segment chronicling occurrences in the Neighborhood of Make-Believe.
At the beginning of each episode, Fred Rogers enters his television studio house, singing "Won't You Be My Neighbor?". He hangs his coat in a closet, puts on a cardigan zipper sweater, and removes his dress shoes to put on sneakers. The reverse would happen at the end of the show with Fred Roger's singing, "Good Feeling."